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Related Experiment Video

Updated: Jun 20, 2026

Murine Kidney Transplant Technique

Murine Kidney Transplant Technique

Published on: October 20, 2015

Nail changes in kidney transplant recipients.

Abeer M Abdelaziz¹, Khaled M Mahmoud, Essam M Elsawy

¹Department of Dermatology, Mansoura University, Mansoura, Egypt.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association

|September 22, 2009

Summary

Kidney transplant recipients (KTR) show a higher prevalence of nail conditions like onychomycosis and Muehrcke's nail compared to healthy individuals. Absent lunula may be a normal variation in Egyptians.

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Area of Science:

Nephrology
Dermatology
Transplantation

Background:

Nail changes are common in end-stage renal disease but rarely reported in kidney transplant recipients (KTR).
Previous studies show conflicting results on the prevalence of onychomycosis in KTR.
This study investigates nail changes in a large cohort of KTR.

Purpose of the Study:

To determine the prevalence and types of nail changes in kidney transplant recipients.
To compare nail pathology in KTR with age- and sex-matched healthy controls.

Main Methods:

A cross-sectional study included 302 KTR and 302 healthy controls.
Nail changes were assessed, and cultures were performed for suspected onychomycosis.
Statistical analysis compared findings between KTR and controls.

Main Results:

40.1% of KTR had nail changes versus 34.4% in controls.
Onychomycosis, Muehrcke's nail, and leuconychia were significantly more prevalent in KTR.
Absent lunula and longitudinal ridging were common in both groups, with no significant difference.

Conclusions:

KTR exhibit increased rates of onychomycosis, Muehrcke's nail, and leuconychia compared to the general population.
Absent lunula might be a normal finding in the Egyptian population.
Regular nail monitoring in KTR is recommended.