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Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

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Related Experiment Video

Updated: Jun 20, 2026

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy (FSM)
19:16

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Published on: August 5, 2009

Electronic speckle-pattern interferometry using single-mode fibers and active fringe stabilization.

J L Santos, T P Newson, D A Jackson

    Optics Letters
    |September 22, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces an all-fiber Michelson interferometer for electronic speckle-pattern interferometry. It compensates for environmental phase coupling in optical fibers, enhancing measurement stability.

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    Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy (FSM)
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    Published on: August 5, 2009

    Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping
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    Implementation of a Reference Interferometer for Nanodetection

    Published on: April 26, 2014

    Area of Science:

    • Optics
    • Interferometry
    • Fiber Optics

    Background:

    • Electronic speckle-pattern interferometry (ESPI) is a powerful optical measurement technique.
    • Environmental factors can induce phase coupling in optical fibers, affecting measurement accuracy.
    • Object and reference illumination are crucial for ESPI.

    Purpose of the Study:

    • To develop an all-fiber system for object and reference illumination in ESPI.
    • To compensate for environmentally induced phase coupling in optical fiber arms.
    • To enhance the stability and reliability of ESPI measurements.

    Main Methods:

    • Utilized an all-fiber Michelson interferometer configuration.
    • Incorporated an electronic servo system for active control.
    • Employed a piezoelectric phase modulator for precise phase adjustments.

    Main Results:

    • Successfully demonstrated compensation for phase coupling in fiber arms.
    • Achieved stable and reliable performance of the interferometer system.
    • Validated the effectiveness of the electronic servo and piezoelectric modulator.

    Conclusions:

    • The developed all-fiber interferometer effectively mitigates environmental disturbances in ESPI.
    • This approach offers a robust solution for stable optical measurements using fiber optics.
    • The system enhances the practical application of electronic speckle-pattern interferometry.