Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Bone Structure01:55

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Classification of Bones01:18

Classification of Bones

The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts— that give the...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preparation and properties of copper-oil-based nanofluids.

Nanoscale research letters·2011
Same author

Ordered gelation of chemically converted graphene for next-generation electroconductive hydrogel films.

Angewandte Chemie (International ed. in English)·2011
Same author

Stereoselective synthesis of highly substituted enamides by an oxidative Heck reaction.

Angewandte Chemie (International ed. in English)·2011
Same author

A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of DNA-functionalized gold nanoparticles.

Chemical communications (Cambridge, England)·2011
Same author

The remarkable enhancement of CO-pretreated CuO-Mn2O3/γ-Al2O3 supported catalyst for the reduction of NO with CO: the formation of surface synergetic oxygen vacancy.

Chemistry (Weinheim an der Bergstrasse, Germany)·2011
Same author

Application of multiwall carbon nanotubes-based matrix solid phase dispersion extraction for determination of hormones in butter by gas chromatography mass spectrometry.

Journal of chromatography. A·2011

Related Experiment Video

Updated: Jun 20, 2026

Unique Approach for Isolating Rat Bone Marrow Neutrophils with Comparable Capacity
08:56

Unique Approach for Isolating Rat Bone Marrow Neutrophils with Comparable Capacity

Published on: April 26, 2024

Multi-variety bone bank in China.

Dan Li1, Long Bi, Guo-Lin Meng

  • 1Institute of Orthopaedics & Traumatology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China. bonebank@fmmu.edu.cn

Cell and Tissue Banking
|September 22, 2009
PubMed
Summary

This Chinese bone bank uniquely develops novel graft materials like reconstituted bone xenograft (RBX) to supplement allografts, addressing donor shortages and viral risks. RBX shows promise in treating fractures and bone defects, even in infected cases.

More Related Videos

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Technique for Isolation and Culture of Rat Jaw Bone Marrow Mesenchymal Stem Cells
04:04

Technique for Isolation and Culture of Rat Jaw Bone Marrow Mesenchymal Stem Cells

Published on: May 31, 2024

Related Experiment Videos

Last Updated: Jun 20, 2026

Unique Approach for Isolating Rat Bone Marrow Neutrophils with Comparable Capacity
08:56

Unique Approach for Isolating Rat Bone Marrow Neutrophils with Comparable Capacity

Published on: April 26, 2024

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
06:59

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Technique for Isolation and Culture of Rat Jaw Bone Marrow Mesenchymal Stem Cells
04:04

Technique for Isolation and Culture of Rat Jaw Bone Marrow Mesenchymal Stem Cells

Published on: May 31, 2024

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Orthopedic Surgery

Background:

  • The establishment of a unique "multi-variety bone bank" in China, founded in 1990.
  • Focus on collecting, processing, and storing allogeneic tissues alongside developing novel graft materials.
  • Challenges with allogeneic tissue supply due to donor limitations and viral transmission risks (HIV, HBV, HCV).

Purpose of the Study:

  • To describe the establishment and operation of a novel Chinese bone bank.
  • To introduce reconstituted bone xenograft (RBX) as a supplementary graft material.
  • To highlight the clinical applications and training initiatives of the institution.

Main Methods:

  • Collection, processing, and deep-frozen storage of allogeneic hemi-joints, preserving biological and mechanical properties.
  • Development and production of non-human derived graft materials, including reconstituted bone xenograft (RBX).
  • Clinical application of RBX and anti-infective reconstituted bone xenograft (ARBX) for various bone conditions.

Main Results:

  • Successful development of RBX with strong osteoinductive capability and no immune rejection.
  • RBX and ARBX demonstrated efficacy in managing old fractures, nonunions, bone defects, and infected osteomyelitis.
  • The institution serves as a key training base for tissue banking professionals and researchers.

Conclusions:

  • The "multi-variety bone bank" model effectively supplements allografts with innovative xenografts like RBX.
  • RBX offers a viable solution for bone reconstruction, particularly in challenging clinical scenarios.
  • The bank plays a crucial role in advancing tissue banking technology and education in China.