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Published on: February 2, 2019
Putting the Invader assay to work: laboratory application and data management
Yi Zhang1, Edward Smith, Michael Olivier
1Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA.
Methods in Molecular Biology (Clifton, N.J.)
|September 22, 2009
Summary
Selecting a single nucleotide polymorphism genotyping method is challenging. This review details how the Invader assay can meet human genomic research needs in a laboratory setting.
Area of Science:
- Genomics
- Molecular Biology
- Biotechnology
Background:
- Choosing appropriate genotyping methods is complex.
- Numerous genotyping technologies are available for research.
- Understanding specific platform capabilities is crucial for experimental design.
Purpose of the Study:
- To provide an end-user perspective on genotyping platforms.
- To evaluate the utility of the Invader assay for human genomic research.
- To guide researchers in selecting suitable genotyping methodologies.
Main Methods:
- Review of commercially available genotyping platforms.
- Focus on the Invader assay's application in a laboratory.
- Discussion from an end-user viewpoint.
Main Results:
- The Invader assay is a viable option for human genomic research.
- The assay can be adapted to meet specific laboratory demands.
- Practical considerations for implementing the Invader assay are discussed.
Conclusions:
- The Invader assay offers a practical solution for single nucleotide polymorphism genotyping.
- Researchers can leverage the Invader assay for human genomic studies.
- Informed selection of genotyping methods is key to successful genetic research.
