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Misdiagnosis of hemicrania continua
Mario F P Peres1, Marcelo M Valença, André Leite Gonçalves
1UNIFESP (Universidade Federal de São Paulo), São Paulo, Brazil. marioperes@yahoo.com
Insights
Hemicrania continua (HC) is an under-recognized headache disorder, often misdiagnosed. Prompt recognition and treatment with indomethacin are crucial for managing this continuous unilateral headache syndrome.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Hemicrania continua (HC) is a primary headache disorder.
- It presents as a continuous, unilateral headache of moderate intensity with severe pain exacerbations.
- Misdiagnosis is common in clinical practice.
Purpose of the Study:
- To bridge the diagnostic gap for Hemicrania continua.
- To highlight HC as an under-recognized headache syndrome.
- To discuss diagnostic criteria and treatment options.
Main Methods:
- Review of existing literature on Hemicrania continua.
- Analysis of clinical characteristics and diagnostic challenges.
- Evaluation of treatment responses, particularly to indomethacin.
Main Results:
- HC is characterized by continuous unilateral pain and complete response to indomethacin.
- It is more common than previously thought and often misdiagnosed.
- Variants like HC with aura exist, and secondary causes may occur.
Conclusions:
- Accurate diagnosis of Hemicrania continua is essential.
- Indomethacin remains the gold standard treatment.
- Increased awareness can improve patient outcomes for this under-recognized headache disorder.
Abstract:
Hemicrania continua (HC) is a primary headache disorder that is characterized by a continuous unilateral headache of moderate severity, exacerbations of severe pain, and complete responsiveness to indomethacin. Misdiagnosis of HC is probably common in general neurology settings and other clinical specialties. This paper is an attempt to bridge the gap between the correct and misdiagnosis of this disorder. HC was once thought to be a rare headache disorder, but is, in fact, an under-recognized headache syndrome. HC can be of continuous or remitting form. Variants such as HC with aura have been described and secondary cases may occur. Indomethacin is the best treatment, although HC could respond to other NSAIDs, such as the selective COX-2 inhibitors.
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