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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

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Related Experiment Video

Updated: Jun 20, 2026

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
09:41

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Published on: October 1, 2020

Restorative therapy in stroke using stem cells.

M V Padma Srivastava1

  • 1Department of Neurology, All India Institute of Medical Sciences, New Delhi-110 029, India. vasanthapadma123@rediffmail.com

Neurology India
|September 23, 2009
PubMed
Summary
This summary is machine-generated.

Neural plasticity offers hope for brain repair after injury. Stem cell transplantation shows promise for restoring function in stroke patients, moving towards complete recovery.

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Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain
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Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain

Published on: January 27, 2022

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Last Updated: Jun 20, 2026

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
09:41

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Published on: October 1, 2020

Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain
06:12

Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain

Published on: January 27, 2022

Area of Science:

  • Neuroscience
  • Regenerative Medicine
  • Neurology

Background:

  • The adult brain's regenerative capacity was historically considered limited.
  • Recent research indicates neural plasticity and neurogenesis in animal models of brain ischemia.
  • Functional recovery after brain injury, especially large strokes, remains a significant challenge.

Purpose of the Study:

  • To explore the potential of neurogenesis and stem cell transplantation for brain repair.
  • To investigate therapeutic strategies for restoring function after ischemic stroke.
  • To evaluate the promise of cell-based restorative therapy.

Main Methods:

  • Review of experimental observations in animal models of global and focal brain ischemia.
  • Analysis of ongoing animal and human trials for cell transplantation therapies.
  • Assessment of rehabilitation measures for localized brain injuries.

Main Results:

  • Neural plasticity and potential for neurogenesis have been experimentally observed.
  • Cell transplantation emerges as a promising approach for repairing the nervous system.
  • Current trials suggest significant hope for restorative therapy after stroke.

Conclusions:

  • Stem cell transplantation offers a unique strategy for brain repair and functional restoration.
  • Therapeutic interventions aim for maximum possible restoration and return to normalcy.
  • Further research and clinical trials are crucial for advancing stroke recovery therapies.