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Bilateral epibulbar xanthomas--a case report.

Khami Satchi1, Michael S Loughnan, Penelope A McKelvie

  • 1Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

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Bilateral epibulbar xanthomatous lesions, rare yellow eye masses, can occur in adults without systemic disease. Surgical excision offers successful treatment for these recurrent ocular findings.

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Area of Science:

  • Ophthalmology
  • Dermatopathology
  • Histiocytic Disorders

Background:

  • Epibulbar xanthomatous lesions are rare ocular tumors.
  • These lesions can present bilaterally in adults.
  • Normal serum lipid profiles do not exclude xanthomatous lesions.

Observation:

  • A 44-year-old male presented with recurrent bilateral yellow epibulbar masses.
  • Histological examination revealed foamy histiocytes and Touton giant cells.
  • Systemic evaluation and serum lipid profiles were normal.

Findings:

  • Xanthomatous epibulbar lesions can be an isolated finding.
  • The lesions demonstrated recurrence after initial excision.
  • Surgical excision resulted in no recurrence at 1-year follow-up.

Implications:

  • Further evaluation for non-Langerhans cell histiocytic diseases and lipid metabolism disorders is warranted.
  • Xanthomatous epibulbar lesions may present without systemic manifestations.
  • Surgical excision is an effective treatment for recurrent xanthomatous epibulbar lesions.