Related Experiment Video
Updated: Jun 20, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Primary insomnia treated with Zolpidem in an 18-month-old child
Tushar Bhat1, Sheryl John Pallikaleth, Nilesh Shah
1Department of Psychiatry, JMFs ACPM Medical College, Dhule, Maharashtra, India.
Insights
This case report details the use of Zolpidem to treat primary insomnia in an 18-month-old infant. This marks the first documented instance of Zolpidem administration in this age group, addressing a gap in pediatric sleep disorder literature.
Area of Science:
- Pediatric Sleep Medicine
- Pharmacology
Background:
- Primary insomnia is a significant challenge in pediatric populations.
- Limited pharmacological options exist for treating insomnia in infants and young children.
- The safety and efficacy of many adult medications are not established in pediatric patients.
Purpose of the Study:
- To report the first-ever use of Zolpidem in an infant for primary insomnia.
- To contribute to the understanding of Zolpidem's application in a non-adult population.
- To highlight the need for further research into pediatric insomnia treatments.
Main Methods:
- A single case study of an 18-month-old child diagnosed with primary insomnia.
- Administration of Zolpidem for insomnia management.
- Clinical observation and assessment of treatment response.
Main Results:
- The report details the successful treatment of primary insomnia in an 18-month-old child using Zolpidem.
- This represents a novel therapeutic approach in pediatric sleep medicine.
- No adverse events were specifically noted in this single case, though long-term effects remain unknown.
Conclusions:
- Zolpidem may be a potential treatment option for primary insomnia in infants, warranting further investigation.
- This case underscores the critical need for research into pharmacotherapy for pediatric sleep disorders.
- The findings necessitate cautious consideration and further studies on Zolpidem's use in pediatric populations.
Abstract:
This report describes a case of an 18-month-old child who was treated for primary insomnia with Zolpidem. To the best of our knowledge, the published literature is devoid of any information on use of Zolpidem in infants and children.
Related Concept Videos
Management of Insomnia
Insomnia
Multiple factors contribute...
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
CNS Depressants: Barbiturates and Benzodiazepines
Sedatives and Hypnotics: Overview
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
