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[Pain in the side].

S Grüne1, A Meier, J Steurer

  • 1Departement für Innere Medizin, Universitätsspital Zürch.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|September 18, 1990
PubMed
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A patient with flank pain was diagnosed with a pancreatic neuroendocrine tumor, hypercalcemia, and hypophosphatemia. Further tests ruled out hyperparathyroidism and pituitary adenoma, suggesting a complex endocrine presentation.

Area of Science:

  • Endocrinology
  • Oncology
  • Nephrology

Background:

  • A 54-year-old patient presented with left flank pain, leading to the discovery of a urethral calculus.
  • Initial investigations revealed hypercalcemia and hypophosphatemia, prompting consideration of hyperparathyroidism.

Observation:

  • Abdominal ultrasound, performed to rule out hydronephrosis, incidentally identified a pancreatic tumor.
  • Fine needle biopsy confirmed the pancreatic tumor as a neuroendocrine tumor.

Findings:

  • Neuroendocrine parameter examinations did not indicate an active secreting process from the pancreatic tumor.
  • Magnetic Resonance Imaging (MRI) of the pituitary gland showed no adenomatous alterations, despite suspicion of multiple endocrine neoplasia.

Implications:

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  • The case highlights a complex clinical presentation potentially involving a non-secreting neuroendocrine tumor and metabolic abnormalities.
  • Further investigation is warranted to elucidate the etiology of the observed hypercalcemia and hypophosphatemia in the absence of clear endocrine overactivity.