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Galinsosides A and B, bioactive flavanone glucosides from Galinsoga parviflora
Sadia Ferheen1, Nighat Afza, Abdul Malik
1Pharmaceutical Research Centre, PCSIR Laboratories Complex, Karachi 75280, Pakistan.
Abstract:
Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.
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