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Cataracta ossea - Ultrastructural and specimen analysis.

Stefan Koinzer1, Pia Scharpenack, Hannelore Katzke

  • 1Department of Ophthalmology, University hospital of Schleswig-Holstein, Campus Kiel, Haus 25, Arnold-Heller-Str. 3, D-24105 Kiel, Germany. koinzer@auge.uni-kiel.de

Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft
|September 24, 2009
PubMed
Summary

Ossification of the lens, a rare event, occurred in a phthisical eye after trauma. Mineral analysis confirmed a mineralized lens undergoing osseous metaplasia, resembling enchondral ossification.

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Area of Science:

  • Ophthalmology
  • Pathology

Background:

  • Intraocular osseous metaplasia is recognized, but lens ossification is exceptionally rare.
  • This case presents a unique instance of lens ossification in a phthisical eye.

Observation:

  • A rock-hard intraocular particle was found in an enucleated phthisical eye.
  • The patient had a history of trauma 36 years prior with unclear lens status.
  • Differential diagnoses included intraocular foreign body versus lens ossification.

Findings:

  • X-ray diffraction analysis identified microcrystalline apatite, indicating a mineralized structure.
  • Histological examination confirmed a mineralized lens that underwent secondary osseous metaplasia.
  • The ossification mechanism appeared similar to enchondral ossification.

Implications:

  • The precise mechanisms of lens osseous metaplasia remain unclear due to limited cases.
  • Lens capsule injury and blood supply availability are potential contributing factors.
  • This case highlights a rare pathological process with potential implications for understanding ocular trauma sequelae.