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Bipolar disorder and ADHD: Clinical concerns.
1University of Toronto, Canada.
CNS Spectrums
|September 24, 2009
Summary
Bipolar disorder and adult attention-deficit/hyperactive disorder (ADHD) share similar characteristics, including high prevalence and heritability. Emerging research suggests common brain regions and neural circuits may underlie both conditions.
Area of Science:
- Neuroscience
- Psychiatry
- Genetics
Background:
- Bipolar disorder and adult attention-deficit/hyperactive disorder (ADHD) exhibit overlapping clinical and etiological features.
- Both conditions are prevalent, often underdiagnosed, and have long-term impacts on individuals and society.
Purpose of the Study:
- To highlight the emerging similarities between bipolar disorder and adult ADHD.
- To underscore the shared neurobiological underpinnings suggested by recent scientific investigations.
Main Methods:
- Review of existing literature on bipolar disorder and adult ADHD.
- Analysis of studies implicating common neural circuits in both conditions.
Main Results:
- Identification of shared characteristics: high prevalence, low detection rates, chronic illness course, high comorbidity, multifactorial causes, and genetic liability.
- Emerging evidence points to common brain regions and neural circuits involved in core features of both disorders.
Conclusions:
- Bipolar disorder and adult ADHD present a similar composite of epidemiological, clinical, and genetic factors.
- Further research into shared neural mechanisms is warranted to improve diagnosis and treatment for both conditions.
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