Related Experiment Video
Updated: Jun 20, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
Congenital tumours involving the head, neck and central nervous system
Elida Vazquez1, Amparo Castellote, Nuria Mayolas
1Department of Pediatric Radiology, Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain. evazquez@vhebron.net
Insights
Congenital intracranial tumors are rare brain tumors in newborns, often found during prenatal screening. Early diagnosis and imaging are crucial for planning potential surgical interventions.
Area of Science:
- Pediatric Radiology
- Neuro-oncology
- Fetal Medicine
Background:
- Congenital intracranial tumors are rare and distinct from adult or older pediatric tumors.
- These tumors are frequently discovered incidentally during routine prenatal ultrasound and fetal MRI scans.
- Paediatric radiologists must be adept at recognizing these lesions for accurate differential diagnosis.
Purpose of the Study:
- To highlight the unique characteristics of congenital intracranial tumors.
- To emphasize the importance of prenatal imaging in diagnosing these conditions.
- To guide prenatal planning and surgical interventions for fetal or neonatal cases.
Main Methods:
- Review of clinical presentations and imaging features of congenital intracranial tumors.
- Analysis of diagnostic approaches using both ultrasound (US) and magnetic resonance imaging (MRI).
- Discussion of prognostic factors and limitations of adjuvant therapies in neonates.
Main Results:
- Congenital intracranial tumors present differently than those in older children.
- Prenatal US and fetal MRI are key detection methods.
- Poor prognosis is often linked to large tumor size and limited treatment options at birth.
Conclusions:
- Congenital head and neck lesions necessitate a thorough imaging strategy.
- Integrated US and MRI techniques are vital for effective prenatal planning.
- Improved imaging guidance can enhance fetal and neonatal surgical outcomes.
Abstract:
Congenital intracranial tumours are uncommon and differ from those occurring in older children in clinical presentation, imaging characteristics and prognosis. These tumours are often detected incidentally on routine prenatal US and/or fetal MRI. Hence, the paediatric radiologist should be familiar with the features of those lesions that should be included in the differential diagnosis. In general, the prognosis of these conditions is poor owing to large tumour size and the limitations of adjuvant therapy at such a young age. Congenital lesions involving the head and neck region require a meticulous imaging approach using both US and MRI techniques to better guide prenatal planning and fetal or neonatal surgical procedures.
Related Concept Videos
Neurulation
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Cryptococcal Meningitis