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Related Experiment Video

Updated: Jun 20, 2026

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Published on: March 25, 2020

Polyneuropathy associated with cholesterol crystal embolism.

Matthias Klein¹, B Hartmann, H J Groene

¹Department of Neurology, University Hospital Munich-Grosshadern, Ludwig-Maximilian University, Marchioninistr. 15, 81377, Munich, Germany. matthias.klein@med.uni-muenchen.de

Neurocritical Care

|September 24, 2009

Summary

Cholesterol crystal embolism, a rare complication of arterial catheterization, can cause severe axonal nerve injury and polyneuropathy. This condition should be considered in patients presenting with multiorgan disease and neurological symptoms post-procedure.

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Area of Science:

Cardiovascular Medicine
Neurology
Nephrology

Background:

Cholesterol crystal embolism is a known complication of arterial catheterization.
It typically manifests as a multiorgan disease affecting kidneys, abdomen, and skin.

Observation:

A patient with hypertension and arteriosclerosis developed muscle weakness, extremity pain, and renal failure post-coronary catheterization.
Neurological symptoms progressed over months, indicating severe axonal nerve injury.

Findings:

Nerve conduction studies and biopsy confirmed severe axonal nerve injury.
Kidney biopsy definitively diagnosed cholesterol crystal embolism.

Implications:

Cholesterol crystal embolism is a potential cause of acute polyneuropathy.
Consider this diagnosis in patients with polyneuropathy and multiorgan disease after arterial procedures.