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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Related Experiment Video

Updated: Jun 20, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Photodermatoses with onset in the elderly.

M Trakatelli1, S Charalampidis, L B Novakovic

  • 1Department of Dermatology and Venerology, Papageorgiou Hospital, Aristotle University School of Medicine, Thessaloniki, Greece. mtrakatelli@hotmail.com

The British Journal of Dermatology
|September 25, 2009
PubMed
Summary
This summary is machine-generated.

Photodermatoses, skin conditions triggered by UV light, increasingly affect the elderly. Chronic actinic dermatitis and drug-induced photosensitivity are common in this demographic.

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Last Updated: Jun 20, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Area of Science:

  • Dermatology
  • Geriatrics
  • Photobiology

Background:

  • Photodermatoses are skin conditions caused by ultraviolet radiation (UVR) and visible light.
  • The aging population presents unique challenges for healthcare systems, particularly regarding age-related skin conditions.
  • Understanding photodermatoses in the elderly is crucial due to demographic shifts.

Purpose of the Study:

  • To review photodermatoses prevalent in the elderly population.
  • To highlight diagnostic approaches for these conditions.
  • To emphasize the growing importance of managing light-induced skin disorders in aging individuals.

Main Methods:

  • Comprehensive literature review focusing on photodermatoses in the elderly.
  • Analysis of diagnostic strategies including history, physical examination, and phototesting.
  • Discussion of common conditions like chronic actinic dermatitis and drug-induced photosensitivity.

Main Results:

  • Photodermatoses are significant health concerns for the aging population.
  • Accurate diagnosis relies on thorough patient history, physical examination, and specific tests.
  • Chronic actinic dermatitis and drug-induced photosensitivity are the most frequent photodermatoses in the elderly.

Conclusions:

  • Photodermatoses represent a growing challenge in geriatric dermatology.
  • Early and accurate diagnosis through appropriate testing is essential for effective management.
  • Healthcare systems must adapt to the increasing prevalence of light-related skin disorders in older adults.