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Updated: Jun 20, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Acute postinfectious pityriasis rubra pilaris: a superantigen-mediated dermatosis]
C Ferrándiz-Pulido1, R Bartralot, P Bassas
1Servicio de Dermatología, Hospital Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, España. 40879cfp@comb.es
Abstract:
Acute postinfectious pityriasis rubra pilaris (PRP) is a variant of juvenile PRP (Griffiths type III) characterized by no family history, an acute course associated with a prior fever, and good prognosis. Clinical features may resemble other superantigen-mediated diseases, such as scarlatiniform rash or staphylococcal scalded skin syndrome, but its histology and treatment are different. We present 4 cases of acute postinfectious PRP that illustrate the clinical features of this uncommon disease and we review possible underlying pathogenic mechanisms.
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