Related Experiment Video
Updated: Jun 20, 2026

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
Published on: February 15, 2015
Evaluating the affective component of the cerebellar cognitive affective syndrome
Uri Wolf1, Mark J Rapoport, Tom A Schweizer
1Department of Psychiatry, University of Toronto, Toronto, Canada.
Abstract:
The authors performed a systematic review and meta-analysis of studies evaluating the affective component of the cerebellar cognitive affective syndrome. Depressive and anxiety symptoms and personality changes were more frequent in patients with spinocerebellar ataxia. Patients with cerebellar lesions were more likely to have depression, deficits in the ability to experience emotions, and behavioral difficulties. A meta-analysis revealed modestly higher scores on the Hamilton Depression Rating Scale (HAM-D) among patients with cerebellar disease. This review highlights the need for cohort studies using noncerebellar comparison groups, more sensitive measures, and appropriate-sized populations with isolated cerebellar lesions to thoroughly assess the affective component of the cerebellar cognitive affective syndrome.
More Related Videos
Related Concept Videos
The Influence of Cognition on Affect
The Influence of Affect on Cognition
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Role of Cerebellum and Prefrontal Cortex in Memory
Cognitive Theories: Schachter-Singer Theory of Emotion
Physiological Arousal and Cognitive Labeling
According to this theory, when an individual experiences physiological...
Lazarus's Cognitive Appraisal Theory
Primary Appraisal:...

