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The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis
1Department of Physiology, University of Toronto, Ontario, Canada.
Human Genetics
|October 1, 1990
Abstract:
DNA encoding the human aminopeptidase N (EC 3.4.11.2) gene (PEPN) was first isolated using rat cDNA probes and then used in Southern analysis of DNA from mouse-human somatic cell hybrids to assign this gene to the long-arm region (q11-qter) of human chromosome 15. This human genomic DNA probe detects a frequent DraIII polymorphism that is a useful marker for human chromosome 15.