Related Experiment Video
Updated: Jun 20, 2026

Murine Full-thickness Skin Transplantation
Published on: January 2, 2017
Resurfacing of the thumb following major skin loss
Abstract:
The repair of areas of skin loss on the hand and in particular on the thumb demands a careful appraisal of the type of tissue used to close the wound. In this report on the closure of avulsed wounds of the thumb, emphasis is placed on the superiority of local pedicle tissue, as compared with pedicle flaps obtained from a distance. Abundant pedicle skin is available on the dorsum of the hand of close partial or complete circumferential defects of the thumb from the level of the metacarpophalangeal joint distally.The main advantage of a local pedicle flap is that the tissue more closely simulates the physical characteristics of volar skin. Neither local nor distant pedicle flaps regain functional sensation. If sensation is essential for satisfactory function it must be supplied by normally innervated volar skin added to the thumb by means of a neurovascular island flap.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Healing II: Complications