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Published on: February 2, 2024
[Chemical constituents from Centipeda minima]
Shoucheng Pu1, Yuanqiang Guo, Wenyuan Gao
1School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Summary
Ten chemical compounds were identified from Centipeda minima, with seven being newly discovered from this plant. This research expands our knowledge of the phytochemistry of Centipeda minima.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Context:
- Centipeda minima is a plant with traditional medicinal uses.
- Understanding its chemical composition is crucial for further research and application.
Purpose:
- To isolate and identify the chemical constituents of Centipeda minima.
- To report novel compounds discovered in this plant species.
Summary:
- Ten compounds were isolated from Centipeda minima using column chromatography and HPLC-ODS.
- These compounds include (-)-cis-chrysanthenol-O-beta-D-glucopyranoside, methy 3,5-dicaffeoylquinate, 3,5-di-O-caffeoyl quinicacid, tricin, 2-amino-4-methyl-pentanoicacid, 2-amino-3-phenyl-propionic acid, 4-amino-4-carboxychroman-2-one, brevilin-A, arnicolide C, and arnicolide D.
- Compounds 1-7 represent the first isolation of these specific chemical entities from Centipeda minima.
Impact:
- This study contributes to the phytochemical knowledge of Centipeda minima.
- The identification of novel compounds may pave the way for discovering new bioactive molecules.
- Provides a foundation for future pharmacological investigations of Centipeda minima constituents.
