Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Psychiatric and nervous disorders].

K Hara1

  • 1Department of Perinato-Gynecology, Kagawa Medical School.

Nihon Sanka Fujinka Gakkai Zasshi
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

Managing epilepsy and schizophrenia during pregnancy requires careful consideration of medication risks and benefits. Continued anticonvulsant therapy is crucial for epilepsy, while antipsychotics are generally considered safe for schizophrenia in pregnancy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1.

The Journal of biological chemistry·1992
Same author

Development and characterization of Porphyromonas gingivalis-specific rat T-cell clones.

Archives of oral biology·1992
Same author

[Tumor associated carbohydrate antigens in bronchoalveolar lavage fluid in patients with diffuse panbronchiolitis].

Nihon Kyobu Shikkan Gakkai zasshi·1992
Same author

[Analysis of urinary tract infections in hospitalized elderly patients, with particular reference to the use of diapers].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1992
Same author

[DNA probe and polymerase chain reaction for detection and identification of mycobacteria].

Kekkaku : [Tuberculosis]·1992
Same author

A rare case of extramedullary plasmacytoma in the mediastinum.

Internal medicine (Tokyo, Japan)·1992

Area of Science:

  • Obstetrics and Gynecology
  • Neurology
  • Psychiatry

Context:

  • Increased incidence of treating pregnant patients with psychiatric and nervous disorders.
  • Historical reluctance to treat due to prejudice and teratogenicity concerns.
  • Improved social acceptance and human rights awareness driving treatment.

Purpose:

  • To discuss the management of pregnancy, delivery, and the neonatal period for women with epilepsy and schizophrenia.
  • To highlight the importance of continued anticonvulsant therapy during pregnancy for epilepsy.
  • To address the safety of antipsychotic medications during pregnancy for schizophrenia.

Summary:

  • Epilepsy affects 0.5% of pregnancies; pregnancy has minimal impact on epilepsy. Anticonvulsant therapy (e.g., phenobarbital, phenytoin) should continue due to higher risks of fetal brain damage from untreated seizures. Trimethadione is contraindicated due to teratogenicity. Regular drug monitoring and postpartum vitamin K assessment are vital. Breastfeeding is permissible, but neonatal withdrawal syndrome must be monitored.

Related Experiment Videos

  • Pregnancy does not significantly affect schizophrenia. Antipsychotic medications like chlorpromazine and haloperidol are considered to have negative teratogenicity in humans, though they may suppress fetal central nervous system function.

    • Impact:

    • Provides guidance on managing common neurological and psychiatric conditions during pregnancy.
    • Emphasizes risk-benefit assessment for medication use in pregnant patients.
    • Aims to reduce adverse fetal and neonatal outcomes associated with untreated maternal disorders.