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Updated: Jun 20, 2026

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice
Published on: March 11, 2020
Glutamatergic neurotransmission in the nucleus tractus solitarii: structural and functional characteristics
Agnès Baude1, Caroline Strube, Fabien Tell
1Centre de Recherche en Neurobiologie-Neurophysiologie de Marseille, Unité Mixte de Recherche 6231, Centre National de la Recherche Scientifique, Université Paul Cézanne, Université de la Méditerranée, Marseille, France.
Abstract:
Glutamate is the main excitatory transmitter in the central nervous system. As such, it plays a major role in transmitting and processing visceral sensory information within the nucleus tractus solitarii (NTS). Here, we review current knowledge on NTS glutamatergic transmission. We describe the main organizational features of NTS glutamatergic synapses as determined by work performed during the last decade using antibodies against glutamate receptors and transporters proteins. In light of these recent neuronatomical findings, we discuss some functional properties of developing and adult NTS glutamatergic synapses.
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