Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Iontronics of nanofluidic conical pores: learning phenomena using voltage pulses.

Nanoscale·2026

Same author

Ion-Track-Etched Membranes as Nanoionic Platforms: Fabrication, Nanoscale Ion Transport, and Device Applications─A Review.

Langmuir : the ACS journal of surfaces and colloids·2026

Same author

Top-down perspectives on cell membrane potential and protein transcription.

Scientific reports·2025

Same author

Nanopores with Ionic Memory in Oscillating Ion Current Signals.

Journal of the American Chemical Society·2025

Same author

Multiple Negative Differential Resistances in Nanofluidic Conical Pores: A Phenomenological Model.

The journal of physical chemistry letters·2025

Same author

Multiple threshold potentials in nanofluidic pores with negative differential resistance.

Journal of colloid and interface science·2025

Search research articles

Related Experiment Video

Updated: Jun 20, 2026

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

Logic gates using nanofluidic diodes based on conical nanopores functionalized with polyprotic acid chains.

Mubarak Ali¹, Salvador Mafe, Patricio Ramirez

¹Technische Universität Darmstadt, Fachbereich Material-u. Geowissenschaften, Fachgebiet Chemische Analytik, Petersenstrasse 23, D-64287 Darmstadt, Germany.

Langmuir : the ACS Journal of Surfaces and Colloids

|September 29, 2009

Summary

Single-track conical nanopores with pH-sensitive groups act as nanofluidic diodes. These pores demonstrate three conductance levels, enabling integration of multiple functions for logic gate applications.

More Related Videos

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Published on: November 1, 2013

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment

Published on: July 12, 2016

Related Experiment Videos

Last Updated: Jun 20, 2026

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Published on: November 1, 2013

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment

Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment

Published on: July 12, 2016

Area of Science:

Nanotechnology
Molecular Engineering
Biophysics

Background:

Nanometer-scaled pores are utilized in separation and sensing.
Biological ion channels exhibit pH-dependent fixed charges crucial for information processing.
Nanofluidic diodes have not been explored for logic devices.

Purpose of the Study:

To investigate single-track conical nanopores functionalized with polyprotic acid chains.
To explore the potential of these nanopores in logic devices.
To propose a logic gate scheme using nanofluidic diodes.

Main Methods:

Functionalization of conical nanopores with polyprotic acid chains.
Characterization of pH-sensitive fixed charge groups.
Analysis of conductance levels in nanofluidic diodes.

Main Results:

The functionalized nanopores exhibit pH-sensitive fixed charge groups.
Three distinct levels of conductance were observed.
These conductance levels allow for the integration of multiple functions on a single device.

Conclusions:

Single-track conical nanopores can be engineered as functional nanofluidic diodes.
The observed conductance levels support their use in logic gate schemes.
This work presents a preliminary application for implementing binary and multivalued logical functions.