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Updated: Jun 20, 2026

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
Published on: August 26, 2011
Autobiographical memory in progressive supranuclear palsy
M Zarei1, H R Pouretemad, T Bak
1Department of Clinical Neurology, University of Oxford, Oxford, UK.
Background:
We aimed to investigate recall of autobiographical memories across lifetime periods in patients with progressive supranuclear palsy (PSP).
Method:
Patients with PSP (n = 10) were given a test of autobiographical and personal semantic information and the Addenbrooke's Cognitive Examination (ACE). The result was compared to 30 matched neurologically intact participants.
Result:
A mild autobiographical memory impairment was observed in PSP without a temporal gradient for the recall of autobiographical or personal semantic information. Performance correlated with verbal fluency in ACE.
Conclusion:
Patients with PSP show mild deficits in autobiographical memory, which is likely to reflect a frontal retrieval deficit.
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