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Sexual dysfunction in subjects with Klinefelter's syndrome
1Andrology Unit and Endocrinology Department of Clinical Physiopathology, University of Florence, 50139 Florence, Italy.
International Journal of Andrology
|September 29, 2009
Summary
Klinefelter
Area of Science:
- Endocrinology
- Urology
- Sexual Medicine
Background:
- Klinefelter's Syndrome (KS) is known for infertility.
- Sexual dysfunction prevalence in KS requires further investigation.
Purpose of the Study:
- Analyze KS prevalence in men with sexual problems.
- Investigate specific correlates of sexual dysfunction in KS.
Main Methods:
- Systematic analysis of 1386 adult male patients consulting for sexual problems.
- Comparison of KS patients with general sample and matched controls.
Main Results:
- 23 (1.7%) subjects with KS identified.
- KS patients were younger and more hypogonadal.
- Hypoactive sexual desire (HSD) association with KS disappeared when matched for testosterone levels.
Conclusions:
- Sexual dysfunction in KS is primarily due to hypogonadism, not the syndrome itself.
- Testosterone substitution may help HSD in KS patients.
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