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Published on: July 26, 2024
Clinical management of motility disorders in children
Cheryl E Gariepy1, Hayat Mousa
1Center for Cell and Developmental Biology, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205, USA. Cheryl.Gariepy@NationwideChildrens.org
Insights
This review covers pediatric gastrointestinal motility disorders, including esophageal achalasia and chronic intestinal pseudo-obstruction. It details current clinical evaluation and management strategies for these complex conditions in children.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
- Clinical Management
Background:
- Esophageal and gastrointestinal motility disorders are common in children.
- These conditions significantly impact pediatric health and require specialized care.
- A comprehensive understanding of their evaluation and management is crucial.
Purpose of the Study:
- To review the current clinical evaluation and management of common pediatric esophageal and gastrointestinal motility disorders.
- To synthesize literature findings and clinical experience from a US pediatric motility center.
- To provide a guide for healthcare professionals managing these conditions.
Main Methods:
- Literature review of pediatric gastrointestinal motility disorders.
- Analysis of clinical experience from a specialized pediatric motility center.
- Discussion of various specific motility disorders and their management.
Main Results:
- Detailed discussion of esophageal achalasia, gastroparesis, and chronic intestinal pseudo-obstruction.
- Exploration of motility issues post-surgery (fundoplication, congenital atresia repair, gastroschisis, intestinal transplantation, Hirschsprung's disease resection).
- Coverage of chronic functional constipation and motility disorders associated with imperforate anus.
Conclusions:
- Effective management of pediatric GI motility disorders requires a multidisciplinary approach.
- Early and accurate diagnosis is key to improving patient outcomes.
- Continued research and experience sharing are vital for advancing care.
Abstract:
We review the current clinical evaluation and management of the most common esophageal and gastrointestinal motility disorders in children based on the literature and our experience in a pediatric motility center in the United States. The disorders discussed include esophageal achalasia, pre- and post-fundoplication motility disorders, gastroparesis, motility disorders occurring after repair of congenital atresias, motility disorders associated with gastroschisis, chronic intestinal pseudo-obstruction, motility after intestinal transplantation, motility disorders after colonic resection for Hirschsprung's disease, chronic functional constipation, and motility disorders associated with imperforate anus.
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