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Updated: Jun 20, 2026

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Thrombolysis administration by nurses: An evolving UK evidence base?

M Sloman¹, G R Williamson

¹Cardiology, Royal Devon and Exeter Hospital, NHS Foundation Trust, Exeter, Devon EX2 5DW, UK.

International Emergency Nursing

|September 29, 2009

Summary

Nurse-led thrombolysis safely and effectively reduces door-to-drug times for myocardial infarction patients. This approach is supported by professionals and improves emergency care delivery.

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Last Updated: Jun 20, 2026

Prehospital Thrombolysis: A Manual from Berlin

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Published on: January 15, 2017

Area of Science:

Cardiology
Emergency Medicine
Nursing Practice

Background:

Myocardial infarction (MI) affects 240,000 people annually in the UK.
Thrombolytic agents are crucial for reducing MI damage, morbidity, and mortality.
Timely administration of thrombolysis is vital, with UK policy aiming to minimize delays.

Purpose of the Study:

To systematically review the development of nurse-administered thrombolysis.
To evaluate this practice in the context of UK government policy.
To assess the research evidence on nurse thrombolysis since 2003.

Main Methods:

Systematic literature review.
Inclusion of six relevant papers.
Thematic analysis of study findings.

Main Results:

Nurses safely administer thrombolysis.
Nurse-led services significantly improve door-to-drug times.
Nurse thrombolysis is perceived positively by healthcare professionals.

Conclusions:

Nurses are accurate and safe in diagnosing and treating acute MI.
Nurse-led thrombolysis demonstrably reduces treatment delays.
Effective nurse thrombolysis requires strong local clinical leadership and protocols for 24/7 emergency care.