Related Experiment Videos
Applicability of Pascal distribution to quantal analysis for non-stationary release of neurotransmitter
M Higashima1, S Sawada, C Yamamoto
1Department of Physiology, Faculty of Medicine, Kanazawa University, Japan.
Neuroscience Letters
|July 31, 1990
Abstract:
In order to assess the applicability of theoretical distributions to statistical analysis of neurotransmitter release, we made mathematical approaches such as derivation of frequency-generating function of the distributions, and obtained a result that a frequency distribution of the number of quanta released by the consecutive stimulations is described by a Pascal distribution when the Poisson parameter m varies temporally according to a gamma (gamma) distribution. Therefore, if the experimentally obtained distribution fits with a Pascal distribution, this suggests that non-stationary nature of the release mechanism.