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Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma

Hsu-Feng Lu1, Hai-Lung Wang, Ying-Ying Chuang

  • 1Department of Clinical Pathology, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan.

Neurochemical Research
|September 29, 2009
PubMed

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Cells respond to damage and stress through highly coordinated processes that decide whether they survive or undergo controlled self-destruction. Two major pathways involved in this regulation are apoptosis, a type of programmed cell death, and autophagy, a survival mechanism that helps cells adapt to adverse conditions.ApoptosisApoptosis removes aged or injured cells to maintain tissue balance. During this process, the cell shrinks, chromatin condenses and fragments, and membrane-bound...