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Related Experiment Video

Updated: Jun 20, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Coeliac disease associated with psoriasis.

S Birkenfeld¹, J Dreiher, D Weitzman

¹Clalit Health Services, Tel-Aviv, Israel.

The British Journal of Dermatology

|September 30, 2009

Summary

Patients with psoriasis have a higher prevalence of coeliac disease (CD). This suggests a potential link, and doctors should consider screening psoriasis patients for undiagnosed CD.

Area of Science:

Dermatology
Gastroenterology
Immunology

Background:

Psoriasis is a chronic inflammatory skin condition linked to systemic comorbidities.
Coeliac disease (CD) is an autoimmune disorder triggered by gluten.
The association between psoriasis and CD requires further investigation.

Purpose of the Study:

To determine the prevalence of CD in patients with psoriasis.
To compare CD rates in psoriasis patients versus controls.
To analyze the association between psoriasis and CD.

Main Methods:

A case-control study design was employed.
Data was sourced from the Clalit Health Services medical database.
Statistical analyses included chi-squared tests, t-tests, and logistic regression.

Related Experiment Videos

Last Updated: Jun 20, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Main Results:

The study involved 12,502 psoriasis patients and 24,285 controls.
CD prevalence was significantly higher in psoriasis patients (0.29%) than controls (0.11%, P < 0.001).
Multivariate analysis indicated psoriasis is associated with CD (OR 2.73, 95% CI 1.65-4.53).

Conclusions:

Psoriasis patients exhibit a greater prevalence of coeliac disease.
Undiagnosed CD may be present in a subset of psoriasis patients.
Healthcare providers should consider screening psoriasis patients for CD.