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Published on: October 2, 2016
[Intoxication with Monkshood (Aconitum napellus)]
Rinske M Tuinema1, Ruben Uijlings, Marieke A Dijkman
1Afd. Spoedeisende Hulp, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands.
Nederlands Tijdschrift Voor Geneeskunde
|September 30, 2009
Summary
Aconitum napellus (Monkshood) poisoning can cause severe ventricular arrhythmias, even from accidental ingestion or skin exposure. Treatment is supportive, as no antidote exists for this dangerous plant toxin.
Area of Science:
- Toxicology
- Cardiology
- Botany
Background:
- Aconitum napellus, known as Monkshood or Wolfsbane, contains potent alkaloids.
- These toxins can cause significant cardiovascular and neurological effects.
Observation:
- Three cases of Aconitum napellus intoxication are presented: accidental ingestion, cutaneous exposure, and intentional ingestion.
- Symptoms ranged from severe ventricular tachyarrhythmias to localized skin irritation.
Findings:
- Aconite alkaloids induce ventricular arrhythmias through prolonged sodium channel activation.
- No specific antidote exists; treatment focuses on supportive care for cardiac and respiratory complications.
Implications:
- Healthcare providers should be aware of Aconitum napellus toxicity, especially in cases of unexplained arrhythmias.
- Prompt recognition and supportive management are crucial for improving patient outcomes in Monkshood poisoning.
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