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Related Concept Videos

Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

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Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.

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[Pain management during labour--an informed choice].

Toine Lagro-Janssen1

  • 1Universitair Medisch Centrum St Radboud, afd. Huisartsgeneeskunde, onderafd. Vrouwenstudies Medische Wetenschappen, Nijmegen, The Netherlands. a.lagro-janssen@hag.umcn.nl

Nederlands Tijdschrift Voor Geneeskunde
|September 30, 2009
PubMed
Summary
This summary is machine-generated.

Every laboring woman deserves adequate pain relief upon request. The Dutch guideline supports informed choices, emphasizing shared decision-making between women and healthcare providers for a better birth experience.

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Area of Science:

  • Obstetrics and Gynecology
  • Pain Management
  • Public Health Guidelines

Context:

  • Dutch practice guideline on pharmaceutical pain treatment during labor.
  • Addresses physician and midwife hesitancy in offering labor pain relief.
  • Highlights factors influencing birth satisfaction beyond pain, such as control and fear.

Purpose:

  • To ensure adequate pain treatment for all laboring women upon request.
  • To promote informed choice in pain management during childbirth.
  • To emphasize the collaborative decision-making process between women and healthcare providers.

Summary:

  • The guideline mandates adequate pain relief for laboring women.
  • It acknowledges and addresses professional reservations about administering pain relief.
  • It redefines birth satisfaction, focusing on control, reduced fear, and shared decision-making.

Impact:

  • Empowers women to make informed choices about their labor pain management.
  • Encourages active participation of women in the decision-making process.
  • Aims to improve the overall birth experience by addressing psychological and relational aspects.