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Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures

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Published on: December 22, 2014

Keratoconus associated with the Pierre Robin sequence.

Ming-Lee Lin¹, Vishal Jhanji, Rasik B Vajpayee

¹Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association

|September 30, 2009

Summary

This summary is machine-generated.

This case report details a patient with Pierre Robin sequence who developed acute corneal hydrops, a sign of keratoconus. The findings suggest a potential link between these conditions, impacting visual rehabilitation.

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Area of Science:

Ophthalmology
Genetics

Background:

Pierre Robin sequence is a congenital condition characterized by micrognathia, glossoptosis, and airway obstruction.
Keratoconus is a progressive eye disorder where the cornea thins and bulges outward.

Observation:

A 30-year-old female with known Pierre Robin sequence presented with acute unilateral corneal hydrops.
This was the initial presentation of bilateral keratoconus in the patient.

Findings:

The patient's visual prognosis was poor due to central corneal opacity and contact lens intolerance.
Keratoplasty was not an option due to severe mental retardation.

Implications:

This case highlights a potential association between keratoconus and Pierre Robin sequence.
Further research may elucidate the underlying mechanisms and genetic factors involved.
This association could influence the long-term ophthalmic management of patients with Pierre Robin sequence.