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Published on: September 20, 2018
A case of neuro-Behcet's disease presenting with lumbar spinal cord involvement
1Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Study Design:
Case report.
Objectives:
To report an unusual case of neuro-Behcet's disease (NBD) presenting with isolated myelitis that affected the lumbar cord.
Setting:
Department of Neurology, West China Hospital, Chengdu, Sichuan, China.
Methods:
A 19-year-old man presented with a 3-day history of paresthesia and weakness in both the legs. He had a 6-year history of recurrent oral and genital ulcers with erythema nodosum on his legs. Magnetic resonance imaging (MRI) revealed a T1-hypointense and T2-hyperintense lesion at the L1 level. Nodular enhancement of the lesion was achieved with gadolinium administration. Biopsy specimens from cutaneous lesions were consistent with an active perivasculitic process.
Results:
Corticosteroid (pulsed methylprednisolone followed by oral prednisolone) therapy was administered immediately. Subsequently, the patient's clinical condition improved dramatically. The spinal cord lesion disappeared on the MRI performed 1 year later. Thus far, there has been no recurrence.
Conclusion:
NBD may involve the lumbar spinal cord. Prompt recognition of this disease and early vigorous steroid therapy are important to prevent further disability and recurrence.
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