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Updated: Jun 20, 2026

Establishing a Physiologic Human Vascularized Micro-Tumor Model for Cancer Research
Published on: September 15, 2023
Systems biology and cancer prevention: all options on the table
Simon Rosenfeld1, Izet Kapetanovic
1DHHS/NIH/National Cancer Institute/Division of Cancer Prevention, EPN, 6130 Executive Blvd, Bethesda, MD 20892, USA. sr212a@nih.gov
Abstract:
In this paper, we outline the status quo and approaches to further development of the systems biology concepts with focus on applications in cancer prevention science. We discuss the biological aspects of cancer research that are of primary importance in cancer prevention, motivations for their mathematical modeling and some recent advances in computational oncology. We also make an attempt to outline in big conceptual terms the contours of future work aimed at creation of large-scale computational and informational infrastructure for using as a routine tool in cancer prevention science and decision making.
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