[Hemodynamic changes with sufentanil-oxygen anesthesia for open heart surgery--a comparison of patients with...

We investigated hemodynamic changes in patients undergoing coronary artery bypass grafting (CABG) and valve replacement. The former had been medicated with beta-blocking agent until the morning of operative day. On the other hand, the latter received no medication. We measured systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), heart rate, and rate pressure product (RPP) at the following five points; before induction of anesthesia, immediately before intubation, immediately after intubation, one minute after skin incision and one minute after sternotomy. In both groups, SAP and DAP decreased significantly after induction; heart rate did not change during our study; and RPP decreased significantly after skin incision. There were no significant differences between the group with beta-blocking agent and the group without it. These results suggest that beta-blocking agents exert no influence in our study, and sufentanil-oxygen anesthesia produce hemodynamic stability for open heart surgery.