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Updated: Jun 20, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Trends in US hospital admissions for skin and soft tissue infections
John Edelsberg1, Charu Taneja, Marcus Zervos
1Policy Analysis Inc., Brookline, Massachusetts 02445, USA.
Abstract:
Using data from the 2000-2004 US Healthcare Cost and Utilization Project National Inpatient Sample, we found that total hospital admissions for skin and soft tissue infections increased by 29% during 2000-2004; admissions for pneumonia were largely unchanged. These results are consistent with recent reported increases in community-associated methicillin-resistant Staphylococcus aureus infections.
Insights
Hospital admissions for skin infections rose 29% from 2000-2004. Pneumonia admissions remained stable, aligning with rising community-associated methicillin-resistant Staphylococcus aureus infections.
Area of Science:
- Infectious Diseases
- Epidemiology
- Health Services Research
Background:
- Skin and soft tissue infections (SSTIs) represent a significant public health concern.
- Increases in community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have been reported.
- Understanding trends in hospital admissions for infections is crucial for resource allocation and public health planning.
Purpose of the Study:
- To analyze trends in US hospital admissions for skin and soft tissue infections (SSTIs) between 2000 and 2004.
- To compare these trends with hospital admissions for pneumonia during the same period.
- To assess the potential correlation between SSTI admission trends and the rise of CA-MRSA.
Main Methods:
- Utilized data from the Healthcare Cost and Utilization Project (HCUP) National Inpatient Sample (NIS) for the years 2000-2004.
- Analyzed total hospital admissions for skin and soft tissue infections and pneumonia.
- Calculated percentage changes in admission rates over the study period.
Main Results:
- Total hospital admissions for skin and soft tissue infections increased by 29% from 2000 to 2004.
- Hospital admissions for pneumonia showed no significant change during the study period.
- The observed increase in SSTI admissions is consistent with reported increases in CA-MRSA.
Conclusions:
- Hospitalizations for skin and soft tissue infections significantly increased in the early 2000s.
- The findings suggest a potential link between the rise in SSTIs and the increasing prevalence of methicillin-resistant Staphylococcus aureus.
- Further research is warranted to investigate the specific drivers and implications of these trends.
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