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Ocular involvement in brucellosis.

Gulten Karatas Sungur1, Dicle Hazirolan, Yunus Gurbuz

  • 11st Ophthalmology Department, Ankara Training and Research Hospital, Ankara, Turkey.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|October 1, 2009
PubMed
Summary

Ocular brucellosis affects 21% of patients, with anterior uveitis and choroiditis being most common. Early ophthalmic screening and treatment are crucial for managing this infectious disease.

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Published on: August 5, 2016

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Rheumatology

Background:

  • Brucellosis is a zoonotic infection prevalent in endemic areas.
  • Ocular manifestations can significantly impact patient vision and quality of life.

Purpose of the Study:

  • To document the spectrum of ocular findings in patients diagnosed with brucellosis.
  • To assess the relationship between the stage of brucellosis and specific ocular manifestations.

Main Methods:

  • A prospective cohort study involving 132 patients diagnosed with brucellosis.
  • Ocular examinations were conducted, and brucellosis diagnosis was confirmed via clinical signs, agglutination tests, and blood cultures.

Main Results:

  • Ocular involvement was observed in 21% of brucellosis patients.
  • Anterior uveitis (41%) and choroiditis (32%) were the most frequent ocular manifestations.
  • Acute brucellosis was associated with anterior uveitis, while chronic brucellosis presented with choroiditis, papilledema, and retinal hemorrhages.

Conclusions:

  • Ocular brucellosis is a common complication in endemic regions, necessitating routine ophthalmic evaluations.
  • Brucellosis should be considered in the differential diagnosis of uveitis and choroiditis, with serologic screening recommended.