Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathways and Roadblocks: Navigating Family-Building for Sexual and Gender Minority People Assigned Male at Birth.

Perspectives on sexual and reproductive health·2026
Same author

Engaging Sexual and Gender Minority (SGM) Communities for Health Research: Building and Sustaining PRIDEnet.

Journal of community engagement and scholarship·2024
Same author

Diverse integrated ecosystem approach overcomes pandemic-related fisheries monitoring challenges.

Nature communications·2021
Same author

Reproductive hyperallometry and managing the world's fisheries.

Proceedings of the National Academy of Sciences of the United States of America·2021
Same author

Spatiotemporal patterns of variability in the abundance and distribution of winter-spawned pelagic juvenile rockfish in the California Current.

PloS one·2021
Same author

Global Retinoblastoma Presentation and Analysis by National Income Level.

JAMA oncology·2020
Same journal

Hematology and Serum Biochemistry Reference Intervals for Captive-Born Owl Monkeys (Aotus nancymae): Effects of Age and Sex.

Journal of medical primatology·2026
Same journal

Application of Mobile 3D C-Arm Technology for Diagnostic Imaging of Cleft Palate in an Adult Rhesus Macaque (Macaca mulatta).

Journal of medical primatology·2026
Same journal

Current Landscape of Neonatal/Infant HIV Research: Preclinical and Translational Perspectives.

Journal of medical primatology·2026
Same journal

Clinical Management of Helicobacter Infection in Captive Baboons (Papio anubis and Papio hamadryas), and Isolation and Molecular Characterization of Three Novel Helicobacter Species.

Journal of medical primatology·2026
Same journal

Vitamin D Levels in Captive Bonnet Macaques.

Journal of medical primatology·2026
Same journal

Evaluation of a Point-of-Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus).

Journal of medical primatology·2026
See all related articles

Related Experiment Video

Updated: Jun 19, 2026

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
08:42

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport

Published on: November 27, 2016

Spontaneous gallbladder pathology in baboons.

J L Slingluff1, J T Williams, L Blau

  • 1College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA.

Journal of Medical Primatology
|October 2, 2009
PubMed
Summary
This summary is machine-generated.

Gallbladder pathology (GBP) affects baboons, with a 1.25% prevalence over 20 years. This study highlights similarities between baboon and human GBP, suggesting baboons as a valuable model for human disease research.

More Related Videos

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques
11:06

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

Published on: May 2, 2017

Related Experiment Videos

Last Updated: Jun 19, 2026

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
08:42

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport

Published on: November 27, 2016

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques
11:06

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

Published on: May 2, 2017

Area of Science:

  • Veterinary Pathology
  • Comparative Pathology
  • Primate Research

Background:

  • Gallbladder pathology (GBP) is an uncommon condition observed in both baboons and humans.
  • Understanding GBP in non-human primates can offer insights into human disease.

Purpose of the Study:

  • To determine the prevalence of gallbladder pathology (GBP) in a baboon population.
  • To identify common types of gallbladder abnormalities in baboons.
  • To explore the potential of baboons as a model for studying human GBP.

Main Methods:

  • Retrospective analysis of 7776 necropsy reports over a 20-year period.
  • Identification and classification of gallbladder abnormalities.

Main Results:

  • A 20-year population prevalence of 1.25% for GBP was identified in baboons.
  • GBP was more frequent in adult female baboons (female to male ratio of nearly 2:1).
  • The most common gallbladder pathologies included cholecystitis (35.1%) and cholelithiasis (29.9%).

Conclusions:

  • Epidemiological similarities exist between gallbladder pathology in baboons and humans.
  • The baboon serves as a potentially reliable animal model for investigating human gallbladder pathology.