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Related Experiment Video

Updated: Jan 9, 2026

Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment

Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment

Published on: June 23, 2019

Simian varicella in old world monkeys.

¹Department of Microbiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA. graywaynel@uams.edu

Comparative Medicine

|October 2, 2009

Summary

Simian varicella virus (SVV) causes disease in nonhuman primates, similar to human shingles. This review covers SVV biology, veterinary disease aspects, and clinical signs for better control.

Area of Science:

Veterinary Virology
Primate Pathology

Background:

Simian varicella virus (SVV) causes erythematous disease in Old World monkeys.
SVV is closely related to human varicella-zoster virus (VZV).
SVV can cause sporadic epizootics in nonhuman primate facilities.

Purpose of the Study:

To review the biology of SVV.
To summarize simian varicella as a veterinary disease.
To inform diagnosis and management of SVV in nonhuman primates.

Main Methods:

Literature review of SVV biology and disease.
Summary of clinical signs and pathogenesis.
Discussion of diagnostic and treatment strategies.

Main Results:

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SVV infection presents with fever, vesicular rash, and hepatitis.
The disease can range from mild to life-threatening, with high morbidity/mortality during epizootics.
SVV establishes lifelong latency, with potential for reactivation.

Conclusions:

Prompt diagnosis is crucial for controlling SVV epizootics.
Early antiviral treatment may be effective.
Understanding SVV biology aids in managing this veterinary disease.