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Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

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Related Experiment Video

Updated: Jun 19, 2026

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
07:02

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy

Published on: September 9, 2020

Apical-sparing Tako-tsubo: a case report.

Gioel Gabrio Secco, Gabriele Dell'Era, Matteo Santagostino

    International Journal of Cardiology
    |October 2, 2009
    PubMed
    Summary

    We report a case of apical-sparing Tako-Tsubo syndrome in a postmenopausal woman. This atypical variant presented with chest pain and elevated troponin but normal coronary arteries, with rapid wall motion recovery.

    Related Experiment Videos

    Last Updated: Jun 19, 2026

    Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
    07:02

    Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy

    Published on: September 9, 2020

    Area of Science:

    • Cardiology
    • Cardiovascular Medicine
    • Clinical Case Reports

    Background:

    • Tako-Tsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, typically presents with apical ballooning.
    • Atypical variants of TTC, including apical-sparing patterns, are increasingly recognized.
    • Understanding these variants is crucial for accurate diagnosis and management.

    Observation:

    • A postmenopausal woman presented with classic symptoms of acute coronary syndrome, including chest pain.
    • Initial investigations revealed elevated cardiac biomarkers (troponin) and regional wall motion abnormalities.
    • Coronary angiography demonstrated normal coronary arteries, excluding obstructive coronary artery disease.

    Findings:

    • The patient exhibited an apical-sparing pattern of left ventricular dysfunction, a variant of Tako-Tsubo syndrome.
    • This pattern was characterized by preserved apical contractility with hypokinesis in the mid-ventricular segments.
    • Left ventricular wall motion normalized completely within 48 hours.

    Implications:

    • This case highlights the importance of considering atypical Tako-Tsubo cardiomyopathy variants in the differential diagnosis of acute chest pain.
    • The apical-sparing pattern may represent a distinct pathophysiological mechanism or a specific clinical presentation of TTC.
    • Prompt recognition and appropriate management can lead to favorable outcomes, as demonstrated by the rapid recovery in this patient.