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Bipolar Disorder01:30

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Borderline Personality Disorder01:25

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Related Experiment Video

Updated: Jun 19, 2026

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
09:12

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

Published on: March 17, 2019

Impulsivity, personality and bipolar disorder.

M Lewis1, J Scott, S Frangou

  • 1Section of Neurobiology of Psychosis, PO66 Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK.

European Psychiatry : the Journal of the Association of European Psychiatrists
|October 2, 2009
PubMed
Summary

Impulsivity is not a stable trait in bipolar disorder (BD). Instead, symptom severity, not personality traits, significantly predicts impulsivity, even in those with subsyndromal symptoms.

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Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
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Developing a Rat Model for Bipolar Disorder
04:42

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Impulsivity is a key feature of manic episodes in bipolar disorder (BD).
  • It remains unclear if impulsivity is a persistent trait in BD, present even during remission.
  • The interplay between personality dimensions and impulsivity in BD requires further investigation.

Purpose of the Study:

  • To investigate the relationship between impulsivity, clinical status, and personality traits in patients with bipolar disorder (BD).
  • To determine if impulsivity is a trait feature of BD or associated with active symptoms.

Main Methods:

  • 106 patients with BD and matched healthy volunteers were assessed using the Barratt Impulsiveness Scale (BIS-11) and Eysenck Personality Questionnaire (EPQ).
  • Clinical status was evaluated using standardized scales for mania, depression, and global impression.
  • Patients were categorized into remitted, subsyndromal, and syndromal groups based on symptom severity.

Main Results:

  • No significant differences in impulsivity (BIS-11) or personality (EPQ) scores were found between remitted BD patients and healthy controls.
  • Subsyndromal and syndromal BD patients exhibited elevated scores for impulsivity, Neuroticism, and Psychoticism.
  • Within the BD group, symptom severity was the primary predictor of impulsivity, followed by Psychoticism and Neuroticism.

Conclusions:

  • Increased impulsivity may not be a stable trait characteristic of bipolar disorder (BD).
  • Symptom severity is the most crucial factor influencing impulsivity, even in individuals with subsyndromal BD symptoms.