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Updated: Jun 19, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
Published on: October 3, 2025
Abstract:
Nigel Sharp, national engineering and estates manager at Spire Healthcare, says engineering has never enjoyed a stronger focus at the UK private healthcare provider and its predecessor BUPA Hospitals than it does today. In the past year Spire, with its CEO's strong personal backing, has begun implementing an ambitious new engineering strategy which should provide significantly greater visibility of the condition of key assets in the short-term, while in the longer-term significantly benefiting the group's bottom line. Jonathan Baillie reports.
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Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
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In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...
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In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...

