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Published on: December 2, 2015
Relationship between blood cholesterol level and acute depression
Tahia A Maimanee1, Safyia Al-Hazmi
1Department of Biology, Collage of Science, Kingdom Abdel Aziz University, P.O. Box: l1853 Jeddah 21463, Saudi Arabia. tmaimani@kau.edu.sa
Insights
This study found a strong link between acute depression and lower cholesterol levels. Young adults and widowed or divorced individuals showed higher risks of depression with low cholesterol.
Area of Science:
- Psychiatry and Clinical Psychology
- Biochemistry and Metabolic Disorders
Background:
- Depression is a prevalent psychiatric disorder affecting a significant portion of the population.
- Previous research suggests a correlation between depression and altered cholesterol levels.
Purpose of the Study:
- To investigate the relationship between the severity of depression and blood cholesterol levels.
- To identify demographic and social factors associated with depression and low cholesterol.
Main Methods:
- Blood samples were collected from 144 depressed patients, categorized into acute (60) and mild (84) depression groups.
- Cholesterol levels were measured, and patient data including social and financial status were collected.
- Statistical analysis was performed to determine correlations between depression severity, cholesterol, and demographic factors.
Main Results:
- A significant inverse relationship was observed between acute depression and blood cholesterol levels (below 160 mg/dl).
- Younger individuals were more susceptible to acute depression with low cholesterol.
- Divorced and widowed individuals exhibited a higher likelihood of acute depression with low cholesterol.
Conclusions:
- The findings support the hypothesis linking acute depression with reduced blood cholesterol.
- Specific demographic groups, including youth and those with certain marital statuses, are at increased risk.
- Further research into the biochemical mechanisms underlying this association is warranted.
Abstract:
Depression is regarded as one of the widespread psychiatric diseases. Most probably none is free from depression. A number of researches recorded the relationship between acute depression and reduction in the level of cholesterol of depressed people. In this study, blood samples were collected from 144 depressed subjects, some were visiting, and others were residents in the Psychological Health Hospital and King Fahd Hospital in Jeddah. The necessary tests were carried out on these samples in order to know the level of cholesterol. They were categorized into two groups: subjects with acute depression (60 patients), and those with mild depression (84 patients) according to the criteria of the physician and the psychiatrist in the hospital. Data collected from each patient included the social status, financial status and other information. The results showed a close relationship between acute depression and reduction in blood cholesterol (less than 160 mg/dl). This study is compatible with others that confirm the hypothesis declaring the close relationship between acute depression and low blood cholesterol. The results also showed that the youth category was more exposed to acute depression with low level of cholesterol than the other categories. Also, the sex differences did not affect the incidence of depression, as it was comparable in men and women. However, when age and sex were grouped together, men in the age group of 51-60 years were more exposed to acute depression with low level of cholesterol than women. Besides, the social perspective showed that the divorced and the widowed were more likely to have acute depression accompanied with a low level of cholesterol than other social categories.
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