Related Experiment Video
Updated: Aug 16, 2026

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
Published on: October 2, 2017
Computational study of the conformational structures of saccharides in solution based on J couplings and the "fast
Junchao Xia1, Claudio J Margulis
1Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
Abstract:
This article reports on the implementation of J coupling calculations in our recently developed Fast Sugar Structure Prediction Software (FSPS). The FSPS combines a smart and exhaustive algorithm to search through conformational space with the calculation of different experimental nuclear magnetic resonance observables to establish the conformation of saccharides in solution. Using our algorithm in combination with NMR data, we investigate the solution structure of three simple disaccharides (methyl alpha-sophoroside, methyl alpha-laminarabioside, and methyl alpha-cellobioside) and one complex bacterial polysaccharide (Shigella flexneri 5a).
Related Concept Videos
Chemistry of Carbohydrates
Chemistry of Carbohydrates
Fischer Projections
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Chemistry of Carbohydrates
Biosynthesis of Polysaccharides

