Impact of allergic rhinitis on asthma in children: effects on bronchodilation test

M Capasso1, A Varricchio, G Ciprandi

  • 1Department of Paediatrics, Ospedale Civile "Ave Gratia Plena", Piedimonte Matese, Italy.

Allergy
|October 3, 2009
PubMed

Insights

Children with allergic rhinitis show significant bronchial dilation, indicating a link between upper and lower airways. Bronchodilation testing is recommended for these patients, especially those with longer rhinitis duration.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • The upper and lower airways share a significant relationship.
  • Bronchial obstruction and its reversibility are key diagnostic indicators for asthma.

Purpose of the Study:

  • To evaluate bronchial dilation in children with allergic rhinitis.
  • To identify factors associated with bronchial dilation in this population.

Main Methods:

  • Conducted a study involving 200 children with allergic rhinitis and 150 healthy controls.
  • Utilized clinical examination, skin prick tests, spirometry, and bronchodilation tests.

Main Results:

  • Patients with allergic rhinitis demonstrated a significant increase in FEV(1) post-bronchodilation compared to baseline and controls.
  • Over 20% of rhinitic patients exhibited significant reversibility (≥12% increase).
  • Reversible bronchoconstriction was associated with lower FEV(1), longer rhinitis duration, and perennial allergies.

Conclusions:

  • The study confirms a strong connection between upper (allergic rhinitis) and lower airways.
  • Bronchodilation testing is clinically relevant for children with allergic rhinitis, particularly those with specific characteristics.
Abstract

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