Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fast cyclic voltammetry: measuring transmitter release in 'real time'.

J A Stamford1

  • 1Department of Pharmacology, London Hospital Medical College, U.K.

Journal of Neuroscience Methods
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The canary is dead.

Anaesthesia·2003
Same author

Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of cerebral ischaemia.

British journal of anaesthesia·2001
Same author

Effects of chronic tramadol on pre- and post-synaptic measures of monoamine function.

Journal of psychopharmacology (Oxford, England)·2001
Same author

Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors.

Neuropharmacology·2001
Same author

Multiple 5-HT(1) autoreceptor subtypes govern serotonin release in dorsal and median raphé nuclei.

Neuropharmacology·2001
Same author

Comparison of ketamine stereoisomers on tissue metabolic activity in an in vitro model of global cerebral ischaemia.

Neurochemistry international·2001
Same journal

Time as the language of Behavior: events, sequences, patterns and meanings.

Journal of neuroscience methods·2026
Same journal

Detection of cochlear microphonic for differential diagnosis between auditory neuropathy mice and noise-induced sensorineural hearing loss mice.

Journal of neuroscience methods·2026
Same journal

Assessment metrics for pain control in rats: A methodological commentary.

Journal of neuroscience methods·2026
Same journal

Infant EEG preprocessing pipelines: A capability framework and current gaps in practice.

Journal of neuroscience methods·2026
Same journal

Methods for measuring neural activity during voluntary wheel running.

Journal of neuroscience methods·2026
Same journal

Serotype-dependent differences in AAV cellular transduction rates in the hypothalamus of Arctic ground squirrels.

Journal of neuroscience methods·2026
See all related articles

Fast cyclic voltammetry (FCV) offers high spatial and temporal resolution for real-time monitoring of neurotransmitter release and uptake. This electrochemical technique excels in studying brain function but has limitations in sensitivity and measuring complex signals.

Area of Science:

  • Electrochemistry
  • Neuroscience
  • Analytical Chemistry

Background:

  • Voltammetric methods are crucial for electrochemical analysis.
  • Fast cyclic voltammetry (FCV) presents a unique approach with distinct advantages and limitations.
  • Understanding FCV's capabilities is key for its application in neuroscience.

Purpose of the Study:

  • To delineate the unique characteristics of Fast Cyclic Voltammetry (FCV).
  • To highlight the primary applications and limitations of FCV in neurochemical research.
  • To emphasize the high spatial and temporal resolution offered by FCV.

Main Methods:

  • Utilizes a unique waveform and rapid measurement speed.
  • Incorporates a reduction scan for enhanced analysis.

Related Experiment Videos

  • Facilitates simultaneous unit activity recording at the electrode.

    • Main Results:

    • Achieves high spatial resolution (5 microns) for detailed anatomical analysis.
    • Provides high temporal resolution (25 ms) for real-time measurement of dynamic processes.
    • Demonstrates utility in monitoring ionophoresed/ejected monoamines and stimulated amine release/uptake.

    Conclusions:

    • FCV is a powerful tool for real-time, high-resolution studies of neurotransmitter dynamics in the brain.
    • Its strengths lie in monitoring specific amine release/uptake and studying ascorbic acid function.
    • Limitations include modest sensitivity and inability to measure basal amine levels or complex signals.