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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Published on: June 16, 2020

Work disability in systemic sclerosis.

Marie Hudson1, Russell Steele, Ying Lu

  • 1Sir Mortimer B. Davis-Jewish General Hospital and McGill University, Quebec, Canada. marie.hudson@mcgill.ca

The Journal of Rheumatology
|October 3, 2009
PubMed
Summary
This summary is machine-generated.

Work disability is common in systemic sclerosis (SSc), affecting 21% of patients. Factors like disease severity and duration significantly correlate with disability, highlighting the need for further research into modifiable risk factors.

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Area of Science:

  • Rheumatology
  • Occupational Health

Background:

  • Systemic sclerosis (SSc) is a severe multisystem autoimmune disease.
  • Significant morbidity and mortality are associated with SSc.
  • Work disability in SSc is not well understood.

Purpose of the Study:

  • To determine the prevalence of work disability in a large SSc cohort.
  • To identify demographic and clinical correlates of work disability in SSc patients.

Main Methods:

  • Cross-sectional, multicenter study.
  • Data collected from the Canadian Scleroderma Research Group Registry.
  • Work disability assessed via self-administered questionnaires; logistic regression used for analysis.

Main Results:

  • 21% of 643 SSc patients reported work disability.
  • Work disability increased with disease duration.
  • Significant correlates included comorbidities, disease duration, diffuse disease, severity, pain, fatigue, and physical function.

Conclusions:

  • Work disability is prevalent and occurs early in systemic sclerosis.
  • Markers of disease severity and functional status are associated with work disability.
  • Further research is needed to identify modifiable risk factors.