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Updated: Jun 19, 2026

High-resolution In Vivo Manual Segmentation Protocol for Human Hippocampal Subfields Using 3T Magnetic Resonance Imaging
Published on: November 10, 2015
Normal pituitary stalk: high-resolution MR imaging at 3T.
1Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
High-resolution 3T MRI provides standard measurements for the normal pituitary stalk, aiding in the diagnosis of infundibular lesions. Findings include specific diameters, length, and signal intensity patterns.
Area of Science:
- Radiology
- Neuroimaging
- Endocrinology
Background:
- Accurate assessment of the pituitary stalk is crucial for diagnosing infundibular lesions.
- Higher field strength MRI, such as 3T, may offer improved visualization of the pituitary stalk compared to 1.5T.
Purpose of the Study:
- To evaluate the normal pituitary stalk using high-resolution magnetic resonance imaging (MRI) at 3 Tesla (3T).
- To establish standard measurements for the normal pituitary stalk at 3T.
Main Methods:
- 29 healthy volunteers underwent sagittal MPRAGE and high-resolution oblique-axial T2-weighted MRI at 3T.
- Measurements included pituitary stalk diameter and length, and infundibular recess depth.
- Signal intensity of the pituitary stalk was assessed visually on T2-weighted images.
Main Results:
- Normal pituitary stalk diameters were measured at the pituitary insertion and optic chiasm levels.
- The average length of the pituitary stalk was 5.91 mm, and the infundibular recess depth was 4.69 mm.
- T2-weighted images revealed central hyperintensity with a peripheral rim in 69% of subjects and homogeneous isointensity in 31%.
Conclusions:
- The study provides standard reference measurements for the normal pituitary stalk at 3T MRI.
- Observed signal intensity patterns may correspond to the infundibular stem and pars tuberalis.
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