[Radiobiological properties of progeny of yeast cells, which survive after the thermoradiate exposure]

The delayed effects of the combined action of hyperthermia and ionizing radiation on yeast cells Saccharomyces cereviciae were investigated and compared with analogous effects of gamma-irradiation alone. It was shown that cells, survived after thermoradiate exposure, as well as cells, survived after gamma-irradiation form different in size colonies. The diminishing of size is accompanied by the increasing of the radiosensitivity of cells from these colonies. No significant difference between the radiosensitivity of the progeny of cells, survived the combined exposure, and the radiosensitivity of the progeny of gamma-irradiated cells was observed. A preposition can be made, that the thermal exposure of yeast cells before gamma-irradiation don't practically influence on the delayed effects. The magnitude of recovery (liquid holding recovery) on progeny of surviving cells is essentially smaller then the magnitude of recovery of irradiated parent culture without dependence on the type of initial exposure: combined action or just gamma-irradiation. This magnitude is correlated with the degree of the parental cell damage.